Taken as a whole, the contributions included in this book represent a large body of information that will be of great interest to diabetologists, endocrinologists and internists interested in both the basic and clinical aspects of diabetes ...

eBook Title: Molecular and Cell Biology of Type 2 Diabetes and Its Complications
Author:Francesco Belfiore
Published on 1998-01-01 by Karger Medical and Scientific Publishers


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The present volume summarizes current research on type 2 diabetes, its etiology, pathogenesis and long-term vascular and neurological consequences, with special emphasis on molecular and biochemical mechanisms. Alterations in insulin secretion are comprehensively treated, focusing on the role of glucokinase as glucose sensor. Moreover, insulin action is analyzed with regard to both nonoxidative glucose utilization and glucose oxidation. Concerning the complications in chronic diabetes, topics covered include the effects of high glucose concentration on cellular and endothelial functions and on the glucose phosphorylation rate in non-insulin-sensitive tissues. Furthermore, the role of oxidative stress and advanced glycation end products as well as the significance of alterations in lipoprotein structure are considered. Finally, the pericyte loss in retinopathy and microalbuminuria as related to cardiovascular risk are discussed. Taken as a whole, the contributions included in this book represent a large body of information that will be of great interest to diabetologists, endocrinologists and internists interested in both the basic and clinical aspects of diabetes and its complications.

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Francesco Belfiore
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Book Details:
  1. Book was ranked at 24 by Google Books for Molecular and Cell Biology of Type 2 Diabetes and Its Complications
  2. Molecular and Cell Biology of Type 2 Diabetes and Its Complications published by Karger Medical and Scientific Publishers since 1998-01-01 with ISBNs. The book ISBN 13 Code is 9783805566445 and ISBN 10 Code is 3805566441
  3. Reading Mode in Text Status is false and Reading Mode in Image Status is true
  4. The book has "260 Pages" is Printed at BOOK underMedicalCategory
  5. Rated by 1 Raters and have average rate at "4.0"
  6. eBook Maturity (Adult Book) status is NOT_MATURE
  7. eBook written in en
  8. Book Preview Address: http://books.google.com/books?id=MbRMYDk7p3UC&printsec=frontcover&dq=Diabetes&hl=&cd=103&source=gbs_api

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